To address this issue, we have developed a web-based atlas application in which images of histological sections are integrated with new and up-to-date criteria for subdividing the rat hippocampus formation, fasciola, and associated parahippocampal regions. An overview of both anatomical features and criteria used to delineate boundaries is required to assign location to experimental material from the hippocampal region. Published atlases of the rat brain typically lack the underlying histological criteria necessary to identify boundaries, and textbooks descriptions of the region are often inadequately illustrated and thus difficult to relate to experimental data. The region is complex, consisting of multiple subdivisions that are challenging to delineate anatomically. The rat hippocampal region is frequently studied in relation to learning and memory processes and brain diseases. 3 Department of Anatomy and Neuroscience, VU University Medical Center, Amsterdam, Netherlands.2 Centre for the Biology of Memory, The Kavli Institute for Systems Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.1 Centre for Molecular Biology and Neuroscience, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
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